Weight Management Materials Orlistat is a novel weight loss drug that is not systemic, well tolerated and effective. Treating obesity without appetite suppressants opens up a new avenue for medical treatment of obesity.Orlistat is a long-acting and powerful specific gastrointestinal lipase inhibitor, white or white powder at room temperature, insoluble in water, soluble in chloroform, and soluble in ethanol. It inactivates the enzyme by forming covalent bonds with the active serine sites of gastric lipase and pancreatic lipase in the stomach and small intestine.The fat in food cannot be broken down into free fatty acids and monoacylglycerol, so the fat cannot be absorbed and used by Chemicalbook, thus reducing the body's calorie intake and controlling body weight.The drug works without systemic absorption.Fat absorption can be inhibited by 30% at the usual dose.Rarely absorbed after oral administration, it can be metabolized inactivated in the inte…

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