Ivermectin Injection
This product is a sterile solution prepared from ivermectin, glycerin formal, propylene glycol and other solvents.
Pharmacodynamics: Ivermectin mainly has a good killing effect on nematodes in the body and arthropods on the body surface.
Pharmacokinetics: The pharmacokinetics of ivermectin varies significantly due to different animal species, dosage forms and routes of administration. The bioavailability of subcutaneous injection is higher than that of oral administration, but the absorption of oral administration is faster than that of subcutaneous injection. After absorption, it can be well distributed to most tissues, but it is difficult to enter the cerebrospinal fluid. The apparent volumes of distribution of cattle, sheep and pigs are 0.45-2.4L/kg, 4.6L/kg and 4L/kg, respectively. Most animals have a longer half-life, cattle, sheep and pigs were 2 to 3 days, 2 to 7 days and 0.5 days.
This product is metabolized in the liver, mainly…